Guerreiro cleared to play against Augsburg, Reus and Meunier out
Club captain Marco Reus and Thomas Meunier, by contrast, will both miss out after picking up injuries in Thursday's 2-2 draw with Rangers.
Erling Haaland, Manuel Akanji, Dan-Axel Zagadou and Giovanni Reyna are set to miss the game as well.
Meanwhile, Emre Can is a doubt due to back problems.
"In our final training, Guerreiro was there and has basically been given the green light," said Dortmund coach Marco Rose at the pre-match press conference.
"Reus and Meunier are out, so are the guys who have been missing lately. With Can, we have to see tomorrow how he is doing."